Journal of the Korean Society of Stereotactic and Functional Neurosurgery 2009;5(1):43-46.
Published online June 30, 2009.
Perfusion MRI in Brain Tumor
Dong Moon Jeong, Moo Seong Kim, Sang Wook Joo, Seung Jin No, Seung Hwa Paeng, Young Gyun Jeong, Se Young Pyo, Sun Il Lee, Yong Tae Jung, Hae Woong Jeong
Department of Neurosurgery, Diagnostic Radiology, College of Medicine, Inje University, Busan Paik Hospital, Busan, Korea
Abstract
Objective
It is sometimes difficult to determine the recur of the high grade glioma after operation, radiation therapy, chemotherapy, etc. We assess the usefulness of the perfusion magnetic resonance image (MRI) in the brain tumors. Materials and Methods: We examined 8 patients with histologically verified gliomas (7 with high grade and 1 with low grade glioma.) Conventional MRI demonstrated peripherally enhancing mass with central necrosis and moderate to severe surrounding T2 hyperinternsity suggesting an infiltrating high grade glioma.
Results
Perfusion MRI was performed and demonstrated no hyperperfusion within the lesion and surrounding T2 signal abnormality in the radiation necrosis patients. In three patients, stereotactic biopsy was underwent and showed radiation necrosis.
Conclusion
Perfusion MRI imaging is a useful and reliable technique for diagnosis of the recurred gliomas.
Key Words: Glioblastoma, Perfusion MRI, Recur, Radiation necrosis.
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