| Analysis on Risk Factors of Vascular Complications During Deep Brain Stimulation for Movement Disorders |
|
Seung Joo Lee, Jin Hoon Park, Chang Jin Kim, Sang Ryong Jeon |
|
Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea |
|
|
| Abstract |
Objective
Although deep brain stimulation (DBS) for movement disorders has been regarded as an effective and safe treatment modality, vascular complications may sometimes result in permanent neurological deficits. Risk factors of vascular complications during DBS using microelectrode recording are still being disputed. The authors analyzed the risk factors of vascular complications in a large series of DBS performed at a single institution.
Materials and Methods: From January, 2002 to October, 2005, all DBS surgery cases performed by a single neurosurgeon were included. Postoperative brain computed tomography was done within 24 hours in all cases. All patients with vascular complications were analyzed retrospectively. Correlations between the risk factors which included age, sex, hypertension, target site as well as surgical technique and vascular complications were statistically analyzed using univariate logistic regression, and the validity verification was done using the chi-square test.
Results
A total of 92 procedures were performed in 53 patients. There were seven cases (7.6%) of vascular complications; three intracranial hemorrhage, two intraventricular hemorrhage, one subdural hemorrhage and one cerebral infarction. Among these seven cases, three (3.3%) were neurologically symptomatic and the remaining four were asymptomatic. There was only one case (1.1%) of permanent neurological deficits. Statistical significance was not verified between the occurrence of vascular complications and age, sex, previous history of hypertension, and target site.
Conclusion
DBS using microelectrode can be a relatively safe treatment modality for movement disorders because, in our study, only 1.1% of the permanent neurological deficits were caused by vascular complications. In addition, there was no statistical significant risk factor for vascular complications in DBS surgery in this present study. Further evaluation might be needed when sufficient case addition is accomplished. |
| Key Words:
Deep brain stimulation, Complication, Microelectrode recording, Movement disorder, Subthalamic nucleus, Parkinson disease. |
|
PDF Links
Full text via DOI
Download Citation
