| Variability of the Target Coordinates in Thalamic Deep Brain Stimulation for Epilepsy, Review |
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Jin-gyu Choi, Sung Hoon Kim, Si-hoon Lee, Young-Min Shon, Byung-chul Son |
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Department of Neurosurgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Department of Neurology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea The Catholic Neuroscience Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea |
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| Abstract |
Background
: Deep brain stimulation (DBS) of the thalamus is an emerging treatment for patients with medically refractory epilepsy not suitable for resective surgery.
Objectives : Although an accurate placement of the electrode within thalamic subnucleus is an essential element, the target coordinates in the literatures differ from centers to centers and the descriptions of the target coordinates are often vague. We reviewed the variability of target coordinates of the anterior nucleus of the thalamus (AN) and centromedian nucleus (CM) in the literatures.
Methods
A total of 16 papers met the criteria and were included. The X, Y, Z coordinates and procedural remarks about target planning were summarized.
Results
The X, Y, and Z coordinates for AN varied approximately 3mm in distance. The X and Y coordinates of CM were in range of 3mm in variation. However, the Y coordinates of CM varied widely from 11mm anterior to PC to the anterior level of PC.
Conclusions
Among the reported target coordinates for AN/CM thalamic DBS, the Y coordinates of CM were most variable. Direct visual target selection from MRI was possible for AN, but not for CM. |
| Key Words:
Anterior thalamic nucleus, Centromedian nucleus, Deep brain stimulation, Epilepsy, Thalamus. |
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