| Physical and Radiobiological Aspects of Radiosurgery |
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Hyun-Tai Chung |
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Department of Neurosurgery, Seoul National University Hospital, Seoul, Korea |
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| Abstract |
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Recently, the stereotactic radiosurgery (SRS) is in common use as a substitution or an adjuvant of conventional operation. The
expansion of SRS is based on the accuracy and safety of the systems. In order to understand the characteristics of SRS systems, basic physical phenomena and radiobiological aspects are reviewed. The ionization of the atoms created by the interaction of radiation with a matter causes changes in biological structures. Differences in radiobiological approaches of radiosurgery and conventional radiation therapy are also mentioned. Several SRS modalities are summarized to see advantages of each system. Though these modalities have their own ways to realize the concept of SRS they share the common principle, to focus a radiation to a certain point of the space to bring death or arrest of the cells at the point. It is a hard work to choose one of the systems since their intrinsic characteristics are not to be easily compared directly. But it is possible to choose a suitable system for a patient in a specific condition. The important thing is that we have to understand the basic principle and characteristics of each system to figure out the correct way of application. |
| Key Words:
Stereotactic radiosurgery, Physical principle, Radiobiological Aspects, Radiosurgery modalities. |
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