| Efficacy of Gamma Knife Radiosurgery for Cavernous Sinus Meningioma |
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Han Yu Seong, Jun Bum Park, Soon Chan Kwon, Hong Bo Sim, In Uk Lyo |
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Department of Neurosurgery, University of Ulsan College of Medicine, Ulsan, Korea |
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| Abstract |
Objective
We aimed to determine the efficacy and safety of gamma knife radiosurgery (GKRS) for cavernous sinus meningiomas (CSMs).
Methods
Between May 1991 and September 2003, we used gamma knife radiosurgery for the treatment of 29 patients with cavernous sinus meningiomas. Seventeen patients were followed up for an average of 25.1 months (range, 3-96 mo). The average age of the patients was 42.8 years (range, 16-69 yr). Fourteen patients (82%) underwent operations before radiosurgery, and 3 patients (18%) underwent radiosurgery after the diagnosis was made by magnetic resonance imaging. The tumor volumes ranged from 0.7 to 39.3cm3 (mean, 12.3cm3). The marginal radiation dose was 10 to 17Gy (mean, 13Gy).
Results
Fifteen patients (88.2%) showed tumor growth control during the follow-up period after radiosurgery. Tumor regression
was seen in 5 patients (29.4%) and growth was unchanged in 10 patients (58.8%). Re-growth or recurrence occurred in 2 patients 17.8%). Six patients (35%) had improved clinically at the follow-up examination. None of the patients experienced any new neurological deficits after radiosurgery.
Conclusion
Gamma knife radiosurgery appears to be a safe and effective treatment option for CSMs, not only as an adjuvant to surgery but also as a primary management strategy. |
| Key Words:
Radiosurgery, Cavernous sinus, Meningioma. |
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