Gamma Knife Radiosurgery for Meningioma

Lyo, In Uk; Song, Young; Kim, Jung Hoon; Lee, Do Hee; Kim, Soon Young; Kwon, Do Hoon

Original article

Journal of the Korean Society of Stereotactic and Functional Neurosurgery 2007;3(2):139-142.
Published online September 30, 2007.

Gamma Knife Radiosurgery for Meningioma

In Uk Lyo, Young Song, Jung Hoon Kim, Do Hee Lee, Soon Young Kim, Do Hoon Kwon

Department of Neurosurgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea

Abstract

Purpose
Radiosurgery has become an important treatment option for patients with meningiomas. The author retrospectively reviewed the clinical and radiological data of 247 patients treated with gamma knife radiosurgery (GKRS) for menigiomas between May 1990 and June 2004. Method and Material: Between May 1990 and June 2004, we treated 247 patients with meniongioma using GKRS (male：female ratio, 3：7; mean age, 53 yr; range 16-81 yr). Of them, 102 patients received craniotomy before radiosurgery. 11 patients have got radiosurgery more than one time. 247 patients underwent clinical imaging follow up for a mean period of 67 months (range 2-171 months) after radiosurgery.
Results
Control of tumor growth was achieved in 94% of patients. Side effects were found in 13 patients (6%). Tumor bleeding was found in 4 (2%). 7 patients (3%) were found to have peritumoral edema after gamma knife radiosurgery. Cystic portion was increased in 3 (1%).
Conclusion
Radiosurgical treatment of meningioma is effective and safe to control tumors with acceptable side effects and rate of tumor progression. But, further study is needed to determine the long-term tumor control rates and complications.

Key Words: Meningioma, Radiosurgery, Malignancy.